World · India Bureau
Weight-loss drugs fail for many patients, AIIMS doctors warn
Despite growing use of popular weight-loss medications like Ozempic and Mounjaro, doctors at Delhi's AIIMS are seeing increasing numbers of patients for whom these drugs prove ineffective. Medical experts caution that the medications do not produce uniform results across all patients.
LSN India ·

The use of injectable weight-loss medications, including Ozempic and Mounjaro, has surged across India in recent years, with many seeking pharmaceutical solutions to obesity. However, physicians at the All India Institute of Medical Sciences (AIIMS) report a concerning trend: a significant portion of patients treated with these drugs have failed to achieve meaningful weight reduction.
According to AIIMS doctors, the efficacy of these medications varies substantially from person to person. While some patients experience substantial weight loss, others show minimal or no response despite consistent use of the same pharmaceutical regimen. This variable effectiveness has led to an uptick in patients seeking alternative treatments or further consultation at the institute's obesity management centres.
The medications, which work by mimicking glucagon-like peptide-1 (GLP-1) hormones to regulate appetite and blood sugar, have been widely promoted as game-changing treatments for weight management. However, medical professionals stress that individual factors—including metabolic differences, underlying health conditions, and lifestyle adherence—significantly influence treatment outcomes.
Medical experts advise prospective users to approach these medications with realistic expectations and emphasise the importance of medical supervision. AIIMS doctors recommend comprehensive evaluation and personalised treatment plans rather than relying solely on pharmaceutical interventions for weight management.